The Arble lab is broadly interested in the neuronal intersection between sleep/circadian biology and obesity/diabetes. How the brain controls behavior and disease states is an exciting and growing field with many opportunities to advance our basic understanding as well as develop novel treatment strategies. The Arble lab uses preclinical models to uncover candidate brain regions involved in sleep/circadian biology and obesity/diabetes and utilizes that information to explore novel treatment strategies.
More specifically, the Arble lab has an interest in:
- How does environmental light and/or circadian biology affect breathing behavior?
- How do high-fat diets change our brain and, in turn, change the way we breathe?
The Arble lab currently receives funding from Marquette University, NSF (FAIN#2440777, PI Arble), NIH-NHLBI (R15 HL170276, PI Arble), and the Craig H. Neilsen Foundation (Co-I Arble).
Dr. Arble has been previously funded by:
- Marquette University, Mellon Grant (PI, Arble) “Creative Problem Solving: a new course designed to promote STEM education and discovery”
- American Heart Association, Innovative Project Award 20IPA35320195 (PI, Arble) “Targeting the brain as an effective treatment for sleep apnea.”
- American Heart Association, Scientific Development Grant 17SDG33660108 (PI, Arble) “The role of neuronal leptin in the pathogenesis, and treatment, of sleep apnea and cardiometabolic disease”
- NIH/NIDDK F32 DK097867 (PI, Arble) “Circadian disruption and bariatric surgery: impact on metabolism, clock biology”
- NIH/NIA F31 AG035621 (PI, Arble) “Aging and meal timing interact to exaggerate weight gain”
Arble Lab 