The Arble lab is broadly interested in the neuronal intersection between sleep/circadian biology and obesity/diabetes. How the brain controls behavior and disease states is an exciting and growing field with many opportunities to advance our basic understanding as well as develop novel treatment strategies. The Arble lab uses preclinical models to uncover candidate brain regions involved in sleep/circadian biology and obesity/diabetes and utilizes that information to explore novel treatment strategies.
More specifically, the Arble lab has an interest in:
- Neuronal mechanisms underlying sleep apnea and obesity-associated disordered breathing
- Neuroendocrinology underlying circadian rhythmicity and disruption and the effects on body weight and glucose regulation